Description

Xphos Pd G3 CAS NO 1445085-55-1 is a highly active, third-generation palladium precatalyst featuring the bulky, electron-rich XPhos ligand. This compound matters for its exceptional performance in challenging cross-coupling reactions, offering superior stability and reactivity under mild conditions. It is a critical tool for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and efficient catalysis for complex bond formations.

Application

• Pharmaceutical Intermediate Synthesis: Enabling key C–N, C–O, and C–C bond-forming reactions (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling) in API development.
• Agrochemical Research: Facilitating the synthesis of novel active ingredients through efficient cross-coupling methodologies.
• Materials Science: Used in the preparation of conjugated polymers, organic electronic materials, and functionalized nanomaterials.
• Process Chemistry & Scale-up: Valued for its robustness and consistent performance in optimizing and scaling laboratory reactions to pilot and production scale.
• Academic & Industrial R&D: A preferred catalyst for exploring new synthetic routes and methodologies in organic chemistry.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals, flavors, and fragrances requiring precise catalytic transformations.

Basic Information

Product Name	Xphos Pd G3
CAS No.	1445085-55-1
Molecular Formula	C₄₄H₅₈N₂P₂Pd
Molecular Weight	791.28 g/mol
Synonyms	Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); Pd-PEPPSI-IPent; Palladium PEPPSI-IPent Precatalyst; XPhos Pd G3 Precatalyst; XPhos Palladacycle Gen 3; [2-(2-Aminoethyl)phenyl]chloropalladium-XPhos; XPhos-Pd-G3; Palladium(II) XPhos Precatalyst
EINECS	Contact for details

Quality Control

Our Xphos Pd G3 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to verify identity, purity, and the absence of deleterious impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability. The material is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use.

Specification

Item	Specification
Appearance	Yellow to orange-brown crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Pd Content	12.0 - 14.0 %
Solubility	Soluble in common organic solvents (DCM, THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.