Description

4-Chloro-2,7-Dimethylquinazoline is a high-value, halogenated quinazoline derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for targeted synthesis and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the quinazoline scaffold.
• Organic Synthesis Reagent: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing the quinazoline moiety.
• Material Science Precursor: Potential intermediate in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), and fluorescent dyes.
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Product Name	4-Chloro-2,7-Dimethylquinazoline
CAS No.	1444351-21-6
Molecular Formula	C10H9ClN2
Molecular Weight	192.64 g/mol
Synonyms	4-Chloro-2,7-dimethylquinazoline; 2,7-Dimethyl-4-chloroquinazoline; Quinazoline, 4-chloro-2,7-dimethyl-; 4-Chloro-2,7-dimethyl-quinazoline; 1444351-21-6; 4-Cl-2,7-diMe-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,7-Dimethylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.