Description

1-(Piperidin-4-yl)azetidin-3-ol hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents targeting complex diseases. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly within the fields of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel molecular libraries in drug discovery programs.
• CNS Drug Development: Serves as a precursor for compounds targeting neurological receptors and pathways.
• Oncology Research: Employed in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• Chemical Biology: Utilized as a probe or ligand in studying protein-ligand interactions and biological mechanisms.
• Process Chemistry: Acts as a starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	1-(Piperidin-4-yl)azetidin-3-ol hydrochloride
CAS No.	1443624-48-3
Molecular Formula	C8H17ClN2O
Molecular Weight	192.69 g/mol
Synonyms	1-(Piperidin-4-yl)azetidin-3-ol HCl; 3-Azetidinol, 1-(4-piperidinyl)-, hydrochloride; Azetidin-3-ol, 1-(4-piperidinyl)-, hydrochloride; 1-(Piperidin-4-yl)azetidin-3-ol hydrochloride salt; 1443624-48-3; 1-(4-Piperidyl)azetidin-3-ol hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-yl)azetidin-3-ol hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original container to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.