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2-(((Benzyloxy)Carbonyl)Amino)Pyrimidine-4-Carboxylic Acid CAS NO 1443227-29-9


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CAS No.:1443227-29-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(((Benzyloxy)Carbonyl)Amino)Pyrimidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate crucial for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it serves as a key building block in medicinal chemistry, enabling the development of novel therapeutics with precise molecular architecture. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of antiviral, anticancer, and other small-molecule drug candidates.

Application

  • Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and virology research.
  • Peptidomimetic Synthesis: Used in the construction of peptidomimetics and other biologically active molecules that mimic natural peptides.
  • Chemical Biology Research: Employed as a molecular probe or building block in studying enzyme mechanisms and protein-ligand interactions.
  • API Development: Integral to the research and process development stages for new Active Pharmaceutical Ingredients (APIs).
  • Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name 2-(((Benzyloxy)Carbonyl)Amino)Pyrimidine-4-Carboxylic Acid
CAS No. 1443227-29-9
Molecular Formula C13H11N3O4
Molecular Weight 273.25 g/mol
Synonyms 2-(((Benzyloxy)carbonyl)amino)pyrimidine-4-carboxylic acid; 2-{[(Benzyloxy)carbonyl]amino}pyrimidine-4-carboxylic acid; 2-(N-Cbz-amino)pyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 2-[[(phenylmethoxy)carbonyl]amino]-; Cbz-Amino-pyrimidine-4-carboxylic Acid; Z-Amino-pyrimidine-4-carboxylic Acid; 2-(Carbobenzyloxyamino)pyrimidine-4-carboxylic acid
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Quality Control

Our 2-(((Benzyloxy)Carbonyl)Amino)Pyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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