Description

5-Bromo-3-Hydroxy-2-Methylbenzoic Acid is a halogenated hydroxybenzoic acid derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced material science industries seeking to introduce specific bromine and carboxylic acid functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for incorporating the bromo-hydroxy-benzoic acid scaffold into potential therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where its specific halogen and acid groups are crucial for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers requiring precise bromine and carboxylic acid functionalization.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes and tags used in biochemical and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis organizations (CSOs) and CDMOs producing bespoke compounds for client R&D programs.

Basic Information

Product Name	5-Bromo-3-Hydroxy-2-Methylbenzoic Acid
CAS No.	1442643-22-2
Molecular Formula	C8H7BrO3
Molecular Weight	231.05 g/mol
Synonyms	2-Methyl-5-bromo-3-hydroxybenzoic acid; 3-Hydroxy-2-methyl-5-bromobenzoic acid; 5-Bromo-3-hydroxy-o-toluic acid; Benzoic acid, 5-bromo-3-hydroxy-2-methyl-; 1442643-22-2; 5-Bromo-3-hydroxy-2-methyl-benzoic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Hydroxy-2-Methylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.