Description

7Oxaspiro[3.5]Nonan2Ylmethanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its constrained spirocyclic scaffold.
• Agrochemical Synthesis: Serves as a precursor for developing new generation pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fine Chemical Production: Integral in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Institutional R&D: Used in universities and research institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	7-Oxaspiro[3.5]nonan-2-ylmethanamine
CAS No.	1440962-10-6
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	2-(Aminomethyl)-7-oxaspiro[3.5]nonane; 7-Oxaspiro[3.5]nonane-2-methanamine; (7-Oxaspiro[3.5]nonan-2-yl)methanamine; 1440962-10-6; Spirocyclic amine intermediate; 2-Aminomethyl-7-oxaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Every batch of 7Oxaspiro[3.5]Nonan2Ylmethanamine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomer specified)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.