Description

(5,6,7,8-Tetrahydro-Quinazolin-6-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its quinazoline-derived heterocyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents, such as kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting specific enzymes or receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Used in the construction of quinazoline-based compounds being investigated for their kinase inhibitory activity.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	(5,6,7,8-Tetrahydro-Quinazolin-6-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1440526-58-8
Molecular Formula	C₁₃H₁₉N₃O₂
Molecular Weight	249.31 g/mol
Synonyms	tert-Butyl N-(5,6,7,8-tetrahydroquinazolin-6-yl)carbamate; 6-((tert-Butoxycarbonyl)amino)-5,6,7,8-tetrahydroquinazoline; Boc-6-amino-5,6,7,8-tetrahydroquinazoline; N-Boc-5,6,7,8-tetrahydroquinazolin-6-amine; (5,6,7,8-Tetrahydroquinazolin-6-yl)carbamic acid 1,1-dimethylethyl ester; 1440526-58-8; BOC-THQ-amine
EINECS	Contact for details

Quality Control

Our (5,6,7,8-Tetrahydro-Quinazolin-6-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.