Description

3-Bromo-4-Oxo-1H-Quinoline-6-Carbonitrile is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is of significant value for its role as a key synthon in the development of novel heterocyclic compounds, particularly in medicinal chemistry. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing potential drug candidates and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of quinoline-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic entities.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and insecticides with quinoline scaffolds.
• Organic Light-Emitting Diodes (OLEDs): Potential use as an electron-transport or emissive layer material in electronic device fabrication.
• Coordination Chemistry: Acts as a ligand for metal complexes in catalysis and materials science applications.
• Academic & Industrial R&D: Essential for synthetic organic chemists exploring new heterocyclic reactions and methodologies.

Basic Information

Product Name	3-Bromo-4-Oxo-1H-Quinoline-6-Carbonitrile
CAS No.	1440526-48-6
Molecular Formula	C₁₀H₅BrN₂O
Molecular Weight	249.07 g/mol
Synonyms	3-Bromo-4-oxo-1,4-dihydroquinoline-6-carbonitrile; 6-Cyano-3-bromo-4-hydroxyquinoline; 3-Bromo-4-hydroxyquinoline-6-carbonitrile; 3-Bromo-4(1H)-quinolinone-6-carbonitrile; 1440526-48-6; 3-Bromo-4-oxo-1H-quinoline-6-carbonitrile; 3-Bromo-4-oxo-1,4-dihydro-quinoline-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Oxo-1H-Quinoline-6-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be stored away from light. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.