Description

2-(Trifluoromethyl)Cyclohexanamine Hcl is a high-purity, fluorinated organic building block essential for advanced chemical synthesis. This compound matters for its unique trifluoromethyl group, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by pharmaceutical R&D teams and agrochemical manufacturers developing novel active ingredients, as well as by fine chemical producers serving the electronics and material science sectors.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the CF₃ group enhances biological activity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Incorporated into specialty polymers and advanced organic frameworks to modify thermal and chemical resistance.
• Fluorinated Compound Library: A valuable scaffold for medicinal chemistry and high-throughput screening in drug discovery programs.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical orders.

Basic Information

Product Name	2-(Trifluoromethyl)Cyclohexanamine Hcl
CAS No.	1439905-39-1
Molecular Formula	C₇H₁₃ClF₃N
Molecular Weight	203.63 g/mol
Synonyms	2-(Trifluoromethyl)cyclohexanamine hydrochloride; trans-2-(Trifluoromethyl)cyclohexanamine HCl; 2-(Trifluoromethyl)cyclohexylamine hydrochloride; Cyclohexanamine, 2-(trifluoromethyl)-, hydrochloride; 2-Cyclohexyl-1,1,1-trifluoro-2-propanamine hydrochloride; (1r,2r)-2-(Trifluoromethyl)cyclohexan-1-amine hydrochloride; (1s,2s)-2-(Trifluoromethyl)cyclohexan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Cyclohexanamine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) with full traceability are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (specify isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.