Description

1,7-Diazaspiro[4.4]Nonan-2-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and antiviral applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially those targeting neurological disorders.
• API Synthesis: Serves as a core scaffold for constructing complex molecules in the production of Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization in drug discovery pipelines.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	1,7-Diazaspiro[4.4]Nonan-2-One Hydrochloride
CAS No.	1439902-64-3
Molecular Formula	C7H11N2O·HCl
Molecular Weight	176.64 g/mol
Synonyms	1,7-Diazaspiro[4.4]nonan-2-one, hydrochloride; 2-Oxo-1,7-diazaspiro[4.4]nonane hydrochloride; 1,7-Diazaspiro[4.4]nonan-2-one HCl; Spirocyclic diazepinone hydrochloride; 1,7-Diaza-spiro[4.4]nonan-2-one hydrochloride; 1,7-Diazaspiro[4.4]nonane-2-one hydrochloride; 2H-1,7-Diazaspiro[4.4]nonan-2-one, hydrochloride
EINECS	Contact for details

Quality Control

Our 1,7-Diazaspiro[4.4]Nonan-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.