Description

1-[4-(Trifluoromethyl)Benzyl]-1H-Imidazole-2-Carboxylic Acid is a high-value, multifunctional heterocyclic building block featuring a trifluoromethylbenzyl group and a carboxylic acid moiety. This compound is critical for researchers and manufacturers requiring precise molecular scaffolds with tunable electronic and steric properties. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly as a key intermediate in the development of enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially those targeting specific enzymes or receptors where the imidazole and trifluoromethyl groups are pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique chemical structure to enhance biological activity and environmental stability.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating specialized ligands used in transition metal catalysis, facilitating more efficient and selective chemical transformations.
• Material Science: Employed in the research and development of advanced organic materials, such as organic semiconductors or metal-organic frameworks (MOFs), due to its conjugated system and functional handles.
• Chemical Biology Probes: Acts as a core structure for designing molecular probes and tags used to study biological processes and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies and CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Benzyl]-1H-Imidazole-2-Carboxylic Acid
CAS No.	1439902-58-5
Molecular Formula	C12H9F3N2O2
Molecular Weight	270.21 g/mol
Synonyms	1-[(4-Trifluoromethyl)benzyl]-1H-imidazole-2-carboxylic acid; 1H-Imidazole-2-carboxylic acid, 1-[[4-(trifluoromethyl)phenyl]methyl]-; 1-(4-Trifluoromethylbenzyl)imidazole-2-carboxylic acid; 1-(4-(Trifluoromethyl)benzyl)-1H-imidazole-2-carboxylic acid; 2-Carboxy-1-(4-trifluoromethylbenzyl)imidazole; α-(Trifluoromethyl)benzylimidazole-2-carboxylic acid; 1-(4-Trifluoromethyl-benzyl)-1H-imidazole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[4-(Trifluoromethyl)Benzyl]-1H-Imidazole-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.