Description

(3,3-Difluorocyclopentyl)Methanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique difluorinated cyclopentyl scaffold. This compound is valued for its role in modulating the physicochemical and metabolic properties of active pharmaceutical ingredients (APIs), particularly in drug discovery and development. It is primarily sought by research organizations and manufacturers in the pharmaceutical and agrochemical industries for synthesizing novel therapeutic candidates, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker in the design of chemical probes for target identification and validation studies.
• Material Science: Potential precursor for specialty polymers or advanced materials where the fluorinated structure imparts specific chemical resistance or surface properties.
• Academic & Contract Research: Employed in academic laboratories and CROs (Contract Research Organizations) for method development and exploratory synthetic chemistry.

Basic Information

Product Name	(3,3-Difluorocyclopentyl)Methanamine Hydrochloride
CAS No.	1439900-13-6
Molecular Formula	C6H12ClF2N
Molecular Weight	171.62 g/mol
Synonyms	(3,3-Difluorocyclopentyl)methanamine HCl; 1-(Aminomethyl)-3,3-difluorocyclopentane hydrochloride; 3,3-Difluorocyclopentanemethylamine hydrochloride; (3,3-Difluorocyclopentyl)methylamine hydrochloride; 3,3-Difluorocyclopentylmethanamine hydrochloride; (3,3-Difluorocyclopentyl)methanamine monohydrochloride; 1-(3,3-Difluorocyclopentyl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (3,3-Difluorocyclopentyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.