Description

4-[(3-Chlorophenyl)Methyl]Oxane-4-Carboxylic Acid is a high-purity, synthetically valuable chiral building block and intermediate. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and advanced organic materials due to its unique structural features. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the chlorophenyl moiety for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands used in asymmetric catalysis.
• Material Science: A building block for specialty polymers and liquid crystals, where its rigid oxane-carboxylic acid structure imparts specific properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-[(3-Chlorophenyl)Methyl]Oxane-4-Carboxylic Acid
CAS No.	1439899-48-5
Molecular Formula	C13H15ClO3
Molecular Weight	254.71 g/mol
Synonyms	4-[(3-Chlorophenyl)methyl]tetrahydro-2H-pyran-4-carboxylic acid; 4-((3-Chlorobenzyl)oxy)tetrahydro-2H-pyran-4-carboxylic acid; 4-(3-Chlorobenzyl)tetrahydro-2H-pyran-4-carboxylic acid; 3-Chlorobenzyl tetrahydropyran-4-carboxylate derivative; THP-4-carboxylic acid, 4-(3-chlorobenzyl)-; CAS 1439899-48-5
EINECS	Contact for details

Quality Control

Our 4-[(3-Chlorophenyl)Methyl]Oxane-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.