Description

3-[3-(Aminomethyl)Phenyl]-Tetrahydropyrimidin-2(1H)-One Hydrochloride is a high-purity organic salt compound, primarily utilized as a key pharmaceutical intermediate in advanced synthesis. Its value lies in providing a critical building block for the development of novel therapeutic agents, ensuring reliable supply and consistent quality for complex chemical processes. This product is essential for research institutions and manufacturers in the pharmaceutical and fine chemical industries, particularly those focused on central nervous system (CNS) and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric drug candidates.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules requiring the specific phenyl-tetrahydropyrimidinone pharmacophore.
• Bioconjugation & Probe Development: The aminomethyl group enables its use in creating labeled compounds or conjugates for biochemical and diagnostic research.

Basic Information

Product Name	3-[3-(Aminomethyl)Phenyl]-Tetrahydropyrimidin-2(1H)-One Hydrochloride
CAS No.	1439899-45-2
Molecular Formula	C12H16N3O·HCl
Molecular Weight	255.74 g/mol
Synonyms	3-(3-(Aminomethyl)phenyl)tetrahydropyrimidin-2(1H)-one hydrochloride; 3-(3-(Aminomethyl)phenyl)perhydropyrimidin-2-one HCl; 1,2,3,4-Tetrahydropyrimidin-2-one, 3-[3-(aminomethyl)phenyl]-, hydrochloride; 3-(3-Aminobenzyl)tetrahydropyrimidin-2(1H)-one hydrochloride; 3-(3-(Aminomethyl)phenyl)-1,4,5,6-tetrahydropyrimidin-2(1H)-one hydrochloride
EINECS	Contact for details

Quality Control

Our 3-[3-(Aminomethyl)Phenyl]-Tetrahydropyrimidin-2(1H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.