Description

2-[4-(3-Fluorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is a high-purity fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorinated pyran structure imparts desirable metabolic stability and bioavailability. Pharmaceutical research and development (R&D) departments, agrochemical innovators, and specialty chemical manufacturers are the primary industries that need this precise chemical for their cutting-edge projects.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced polymers and specialty materials with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses serving the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	2-[4-(3-Fluorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid
CAS No.	1439899-08-7
Molecular Formula	C13H15FO3
Molecular Weight	238.26 g/mol
Synonyms	4-(3-Fluorophenyl)tetrahydro-2H-pyran-4-acetic Acid; 2-[4-(3-Fluorophenyl)oxan-4-yl]acetic Acid; 4-(3-Fluorophenyl)-4-(carboxymethyl)tetrahydro-2H-pyran; 2-(4-(3-Fluorophenyl)tetrahydro-2H-pyran-4-yl)acetic Acid; 1439899-08-7; 3-Fluorophenyl-tetrahydropyran-4-yl-acetic Acid
EINECS	Contact for details

Quality Control

Our 2-[4-(3-Fluorophenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.