Description

1-[3-(Trifluoromethyl)Benzyl]Cyclopropylmethanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl-benzyl and cyclopropylamine structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Chemical Research & Development: Serves as a versatile synthon in organic chemistry for constructing complex molecules with cyclopropyl and fluorinated aromatic motifs.
• Ligand & Catalyst Preparation: Employed in the preparation of specialized ligands for catalytic processes and metal-organic frameworks (MOFs).
• Material Science: Potential precursor for the synthesis of functionalized polymers and advanced materials with specific surface properties.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Benzyl]Cyclopropylmethanamine Hydrochloride
CAS No.	1439898-05-1
Molecular Formula	C12H13F3N·HCl
Molecular Weight	255.69 g/mol
Synonyms	N-[(3-Trifluoromethyl)benzyl]cyclopropanemethanamine hydrochloride; 1-[[3-(Trifluoromethyl)phenyl]methyl]cyclopropanemethanamine hydrochloride; Cyclopropanemethanamine, N-[(3-(trifluoromethyl)phenyl)methyl]-, hydrochloride; α-(Cyclopropylmethyl)amino-3-(trifluoromethyl)toluene hydrochloride; 1-[(3-Trifluoromethylbenzyl)amino]methylcyclopropane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Benzyl]Cyclopropylmethanamine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.