Description

3-(4-Fluorophenyl)-2,2-Dimethylpropan-1-Amine Hydrochloride is a high-purity organic salt, specifically a fluorinated amine hydrochloride, valued for its role as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its molecular structure, featuring a fluorinated aromatic ring and a sterically hindered amine, makes it essential for constructing complex molecules with targeted biological activity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new fluorinated compounds.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	3-(4-Fluorophenyl)-2,2-Dimethylpropan-1-Amine Hydrochloride
CAS No.	1439897-98-9
Molecular Formula	C11H16ClFN
Molecular Weight	216.70 g/mol
Synonyms	1-(4-Fluorophenyl)-3,3-dimethylbutan-1-amine hydrochloride; 4-Fluoro-alpha,α-dimethylbenzenepropanamine hydrochloride; 3-(p-Fluorophenyl)-2,2-dimethylpropylamine hydrochloride; 2,2-Dimethyl-3-(4-fluorophenyl)propan-1-amine HCl; 4-Fluoro-α,α-dimethylbenzenepropanamine HCl; 1-Amino-3-(4-fluorophenyl)-2,2-dimethylpropane hydrochloride; p-Fluoro-α,α-dimethylphenethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-2,2-Dimethylpropan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.