Description

1-[3-(Trifluoromethyl)Benzyl]-1H-Imidazol-4-Ylmethanamine Hydrochloride CAS NO 1439897-69-4 is a high-purity, advanced pharmaceutical intermediate characterized by its trifluoromethyl-benzyl-imidazole core structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its imidazole and trifluoromethyl pharmacophores.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of enzyme inhibitors or receptor modulators.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Benzyl]-1H-Imidazol-4-Ylmethanamine Hydrochloride
CAS No.	1439897-69-4
Molecular Formula	C12H13ClF3N3
Molecular Weight	291.70 g/mol
Synonyms	1-[(3-Trifluoromethyl)benzyl]-1H-imidazole-4-methanamine hydrochloride; 4-(Aminomethyl)-1-[(3-(trifluoromethyl)phenyl)methyl]-1H-imidazole hydrochloride; 1-(3-Trifluoromethylbenzyl)-1H-imidazol-4-ylmethanamine HCl; 1H-Imidazole-4-methanamine, 1-[(3-(trifluoromethyl)phenyl)methyl]-, hydrochloride (1:1); 1439897-69-4
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Benzyl]-1H-Imidazol-4-Ylmethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.