Description

2,2-Dimethyl-3-[4-(Trifluoromethyl)Phenyl]Propanoic Acid is a high-value, synthetically versatile organic acid featuring a trifluoromethylphenyl group. This compound is a critical pharmaceutical intermediate and building block in advanced organic synthesis, prized for its ability to impart metabolic stability and lipophilicity to target molecules. It is essential for R&D and production in the pharmaceutical and agrochemical industries, where precise chemical architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing molecules with enhanced bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the trifluoromethyl group for improved activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic displays and optical devices.
• Organic Synthesis Building Block: Employed in medicinal chemistry and material science for introducing the 2,2-dimethylpropanoic acid (pivalic acid) moiety and the aryl-trifluoromethyl group into complex molecules.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	2,2-Dimethyl-3-[4-(Trifluoromethyl)Phenyl]Propanoic Acid
CAS No.	1439896-97-5
Molecular Formula	C₁₂H₁₃F₃O₂
Molecular Weight	246.23 g/mol
Synonyms	3-[4-(Trifluoromethyl)phenyl]-2,2-dimethylpropanoic acid; α,α-Dimethyl-4-(trifluoromethyl)benzenepropanoic acid; 2,2-Dimethyl-3-(4-trifluoromethylphenyl)propionic acid; Pivalic acid, 3-(4-trifluoromethylphenyl)-; 4-(Trifluoromethyl)benzenepropanoic acid, α,α-dimethyl-; (4-Trifluoromethylphenyl)-2,2-dimethylpropanoic acid
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-3-[4-(Trifluoromethyl)Phenyl]Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, appropriate chemical handling procedures should be observed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.