Description

2-(6-Fluoropyridin-3-Yl)Hydrazine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1438599-61-1. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex heterocyclic scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated pyridine-based drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Chemical Synthesis: Serves as a versatile hydrazine derivative for constructing complex heterocycles like pyrazoles and triazoles in academic and industrial R&D.
• Material Science: Potential monomer or precursor for specialty polymers and functional materials requiring fluorinated aromatic units.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	2-(6-Fluoropyridin-3-Yl)Hydrazine Hydrochloride
CAS No.	1438599-61-1
Molecular Formula	C5H7ClFN3
Molecular Weight	163.58 g/mol
Synonyms	2-(6-Fluoropyridin-3-yl)hydrazine hydrochloride; 3-Hydrazinyl-6-fluoropyridine hydrochloride; 6-Fluoro-3-pyridylhydrazine hydrochloride; (6-Fluoropyridin-3-yl)hydrazine HCl; 2-(6-Fluoro-3-pyridinyl)hydrazine hydrochloride; 1438599-61-1; 6-Fluoronicotinohydrazide hydrochloride (related); Hydrazine, (6-fluoro-3-pyridinyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 2-(6-Fluoropyridin-3-Yl)Hydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.