Description

8-Acetyl-5-Chloroquinoline is a high-purity, specialized quinoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. Industries that require it include pharmaceutical R&D for active pharmaceutical ingredient (API) synthesis, agrochemical development, and academic research institutions focused on heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.
• Dye & Pigment Synthesis: Acts as an intermediate for producing specialized quinoline-based colorants and fluorescent markers.
• Ligand Synthesis: Used to create complexing agents and catalysts for metal-mediated chemical transformations.

Basic Information

Product Name	8-Acetyl-5-Chloroquinoline
CAS No.	1438559-55-7
Molecular Formula	C11H8ClNO
Molecular Weight	205.64 g/mol
Synonyms	5-Chloro-8-acetylquinoline; 1-(5-Chloroquinolin-8-yl)ethanone; 8-Acetyl-5-chloroquinoline; 5-Chloro-8-quinolyl methyl ketone; Ethanone, 1-(5-chloro-8-quinolinyl)-; 5-Chloro-8-acetyl-quinoline; 1438559-55-7
EINECS	Contact for details

Quality Control

Our 8-Acetyl-5-Chloroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.