Description

4-((4-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly kinase inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted anticancer and kinase inhibitor drug candidates.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Process Chemistry: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	4-((4-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate
CAS No.	1437310-64-9
Molecular Formula	C17H14FN3O3
Molecular Weight	327.31 g/mol
Synonyms	7-Methoxy-6-acetoxy-4-((4-fluorophenyl)amino)quinazoline; 4-(4-Fluoroanilino)-7-methoxyquinazolin-6-yl acetate; 6-Acetoxy-4-((4-fluorophenyl)amino)-7-methoxyquinazoline; N-(4-Fluorophenyl)-7-methoxy-6-(acetyloxy)-4-quinazolinamine; 4-(p-Fluoroanilino)-7-methoxy-6-acetoxyquinazoline
EINECS	Contact for details

Quality Control

Our 4-((4-Fluorophenyl)Amino)-7-Methoxyquinazolin-6-Yl Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.