Description

5-Bromo-1-Chloro-2-Fluoro-3-Nitrobenzene is a high-purity, multi-substituted aromatic building block of significant importance in advanced organic synthesis. Its unique halogen and nitro substitution pattern makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated benzene core.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments due to its nitro and halogen functional groups.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce the bromo-fluoro-chloro-nitro phenyl moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research and diagnostics.

Basic Information

Product Name	5-Bromo-1-Chloro-2-Fluoro-3-Nitrobenzene
CAS No.	1435806-75-9
Molecular Formula	C6H2BrClFNO2
Molecular Weight	269.44 g/mol
Synonyms	1-Bromo-4-Chloro-5-Fluoro-2-Nitrobenzene; 2-Fluoro-3-Nitro-5-Bromo-1-Chlorobenzene; 3-Nitro-5-Bromo-1-Chloro-2-Fluorobenzene; 5-Bromo-1-Chloro-2-fluoro-3-nitro-benzene; Benzene, 5-bromo-1-chloro-2-fluoro-3-nitro-; 5-Br-1-Cl-2-F-3-NO2-Benzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-Chloro-2-Fluoro-3-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials such as strong oxidizers. Recommended storage temperature: 2-8°C for long-term stability. Keep container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.