Description

trans-3-Amino-2,2-Dimethylcyclobutanol Hcl is a high-purity, structurally defined cyclobutane derivative, serving as a critical chiral building block in advanced organic synthesis. Its rigid, functionalized cyclobutane core is essential for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the synthesis of novel herbicides, fungicides, and insecticides, where its constrained ring structure can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry, including ring-opening and functionalization reactions of strained systems.

Basic Information

Product Name	trans-3-Amino-2,2-Dimethylcyclobutanol Hcl
CAS No.	1434142-03-6
Molecular Formula	C6H14ClNO
Molecular Weight	151.64 g/mol
Synonyms	trans-3-Amino-2,2-dimethylcyclobutanol hydrochloride; (1R,3S)-3-Amino-2,2-dimethylcyclobutanol hydrochloride; (1S,3R)-3-Amino-2,2-dimethylcyclobutanol hydrochloride; 3-Amino-2,2-dimethylcyclobutanol HCl (trans); 2,2-Dimethyl-3-aminocyclobutanol hydrochloride; Cyclobutanol, 3-amino-2,2-dimethyl-, hydrochloride, trans-; 1434142-03-6
EINECS	Contact for details

Quality Control

Our trans-3-Amino-2,2-Dimethylcyclobutanol Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.