Description

6-Bromo-4-(Difluoromethoxy)Quinoline is a high-value, halogenated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both bromine and difluoromethoxy substituents, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline moiety into more complex molecular frameworks.
• Ligand Development: Utilized for constructing novel chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	6-Bromo-4-(Difluoromethoxy)Quinoline
CAS No.	1432754-13-6
Molecular Formula	C₁₀H₆BrF₂NO
Molecular Weight	274.06 g/mol
Synonyms	4-(Difluoromethoxy)-6-bromoquinoline; 6-Bromo-4-(difluoromethoxy)quinoline; Quinoline, 6-bromo-4-(difluoromethoxy)-; 1432754-13-6
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-(Difluoromethoxy)Quinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.