Description

8-Bromo-5-Fluoro-1,2-Dihydroquinolin-2-One is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular modifications in complex organic frameworks. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients, serving as a key intermediate in medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated quinoline structure for bioactivity.
• Material Science Precursor: Serves as a starting material for creating specialized organic ligands, dyes, and functional polymers.
• Chemical Synthesis: Enables Suzuki, Buchwald-Hartwig, and other cross-coupling reactions to introduce complex functionalities into target molecules.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploring new chemical spaces.
• Fluorescent Probe Development: Potential use in creating sensing materials due to the fluorophore-like quinolinone core.

Basic Information

Product Name	8-Bromo-5-Fluoro-1,2-Dihydroquinolin-2-One
CAS No.	1432323-38-0
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	8-Bromo-5-fluoro-2-hydroxyquinoline; 8-Bromo-5-fluoro-1H-quinolin-2-one; 5-Fluoro-8-bromo-1,2-dihydroquinolin-2-one; 2(1H)-Quinolinone, 8-bromo-5-fluoro-; 8-Bromo-5-fluoro-2-quinolinol; 8-Bromo-5-fluoro-2(1H)-quinolinone; 5-Fluoro-8-bromoquinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our production of 8-Bromo-5-Fluoro-1,2-Dihydroquinolin-2-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.