Description

4-Bromo-8-Methyl-1,5-Naphthyridine is a high-purity, halogenated naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for its utility in cross-coupling reactions and as a key synthetic intermediate.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Utilized in various cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the naphthyridine moiety into more complex molecules.
• Ligand Synthesis: Acts as a starting material for the preparation of novel chelating ligands in coordination chemistry and catalysis.
• Academic & R&D: Employed in university and corporate research laboratories for method development and exploring new chemical spaces.

Basic Information

Product Name	4-Bromo-8-Methyl-1,5-Naphthyridine
CAS No.	1432323-27-7
Molecular Formula	C9H7BrN2
Molecular Weight	223.07 g/mol
Synonyms	8-Methyl-4-bromo-1,5-naphthyridine; 4-Bromo-8-methyl-1,5-naphthyridine; 1,5-Naphthyridine, 4-bromo-8-methyl-; 1432323-27-7; 4-Bromo-8-methyl-[1,5]naphthyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-8-Methyl-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.