Description

3-Bromo-8-Fluoroquinolin-6-Amine CAS NO 1432323-09-5 is a high-purity, advanced pharmaceutical intermediate belonging to the halogenated quinoline class of compounds. Its molecular structure, featuring strategically placed bromo and fluoro substituents, makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process scale-up teams in the life sciences sector. It is primarily utilized in the development of next-generation therapeutics targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Research: Used in the development of new fungicides and herbicides due to its bioactive quinoline core.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic frameworks via cross-coupling and amination reactions.
• Biochemical Tool Compound: Used in biochemical assays and as a probe for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	3-Bromo-8-Fluoroquinolin-6-Amine
CAS No.	1432323-09-5
Molecular Formula	C9H5BrFN3
Molecular Weight	254.06 g/mol
Synonyms	6-Amino-3-bromo-8-fluoroquinoline; 8-Fluoro-3-bromoquinolin-6-amine; 3-Bromo-8-fluoro-6-quinolinamine; 1432323-09-5; Quinoline, 6-amino-3-bromo-8-fluoro-; 8-Fluoro-3-bromo-6-aminoquinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-8-Fluoroquinolin-6-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.