Description

4-Methyl-1H-Pyrazol-3-Amine Hydrochloride is a high-purity organic salt derivative of a substituted pyrazole, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a functionalized, protected amine group that is essential for constructing complex heterocyclic frameworks and active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides due to its pyrazole core structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Bioconjugation Chemistry: The amine hydrochloride salt can be utilized in coupling reactions for labeling and modifying biomolecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	4-Methyl-1H-Pyrazol-3-Amine Hydrochloride
CAS No.	1431963-06-2
Molecular Formula	C4H8N3Cl
Molecular Weight	133.58 g/mol
Synonyms	3-Amino-4-methyl-1H-pyrazole hydrochloride; 4-Methyl-1H-pyrazol-3-amine hydrochloride; 4-Methyl-3-pyrazolamine hydrochloride; 1H-Pyrazol-3-amine, 4-methyl-, hydrochloride; 4-Methyl-1H-pyrazol-3-ylamine hydrochloride; 3-Amino-4-methylpyrazole hydrochloride; 4-Methyl-3-aminopyrazole hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-1H-Pyrazol-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.