Description

7-Methyl-1-((trimethylsilyl)oxy)-1,2,3,4-tetrahydronaphthalene-1-carbonitrile (Wxg01542) is a specialized, high-purity organosilicon intermediate featuring a protected cyanohydrin functionality on a partially saturated naphthalene scaffold. This compound is critical for synthetic chemists requiring precise molecular building blocks for complex organic synthesis, particularly in pharmaceutical research and development. Its unique structure makes it a valuable precursor for constructing advanced chemical entities, serving industries focused on fine chemicals, active pharmaceutical ingredients (APIs), and novel material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Fine Chemical Synthesis: Used as a protected cyanohydrin reagent for introducing nitrile and carbonyl functionalities in complex organic molecules under controlled conditions.
• Agrochemical Research: Acts as a building block for developing new active ingredients with enhanced efficacy and environmental profiles.
• Material Science Precursor: Employed in the research and development of specialty polymers and advanced organic electronic materials due to its fused ring and silyl ether groups.
• Academic & R&D Laboratories: Utilized in methodological studies and as a reference standard for reaction development involving silyl-protecting groups and tetralone derivatives.

Basic Information

Item	Details
Product Name	7-Methyl-1-((trimethylsilyl)oxy)-1,2,3,4-tetrahydronaphthalene-1-carbonitrile (Wxg01542)
CAS No.	1431954-24-3
Molecular Formula	C16H23NOSi
Molecular Weight	273.45 g/mol
Synonyms	1-Cyano-7-methyl-1-((trimethylsilyl)oxy)-1,2,3,4-tetrahydronaphthalene; 7-Methyl-1-((trimethylsilyl)oxy)-1,2,3,4-tetrahydro-1-naphthalenecarbonitrile; 1-((Trimethylsilyl)oxy)-7-methyl-1,2,3,4-tetrahydronaphthalene-1-carbonitrile; Wxg01542; TMS-protected 7-methyl-1-cyano-1,2,3,4-tetrahydronaphthalen-1-ol; 7-Methyl-1-trimethylsiloxy-1,2,3,4-tetrahydronaphthalene-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 7-Methyl-1-((trimethylsilyl)oxy)-1,2,3,4-tetrahydronaphthalene-1-carbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%; Any single unknown impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.