Description

(R)-2-Nitro-α-Methylbenzylamine Hydrochloride is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. This compound matters for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic molecules.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental safety.
• Catalyst and Ligand Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Employed in methodological studies and process chemistry research for developing new synthetic routes to chiral amines and nitro compounds.
• Fine Chemical Production: Intermediate in the manufacture of specialty dyes, pigments, and other performance chemicals where the nitro and amine functionalities are essential.

Basic Information

Product Name	(R)-2-Nitro-α-Methylbenzylamine Hydrochloride
CAS No.	1431699-56-7
Molecular Formula	C8H11ClN2O2
Molecular Weight	202.64 g/mol
Synonyms	(R)-1-(2-Nitrophenyl)ethan-1-amine hydrochloride; (R)-α-Methyl-2-nitrobenzylamine hydrochloride; (R)-1-(2-Nitrobenzyl)ethylamine hydrochloride; (R)-2-Nitro-α-methylbenzenemethanamine hydrochloride; (R)-1-Amino-1-(2-nitrophenyl)ethane hydrochloride; (R)-1-(2-Nitrophenyl)ethylamine hydrochloride; Benzenemethanamine, 2-nitro-α-methyl-, (αR)-, hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-2-Nitro-α-Methylbenzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.