Description

cis-2-Methoxycyclopentan-1-Amine Hydrochloride is a high-purity chiral amine hydrochloride salt, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex, biologically active molecules, offering a defined stereocenter for precise molecular construction. Pharmaceutical research and development organizations, particularly those focused on medicinal chemistry and process development, need this material for creating novel therapeutic candidates, including potential central nervous system (CNS) agents and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for CNS-targeted therapies.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to introduce specific stereochemistry and amine functionality into drug-like molecules.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and route development for GMP manufacturing of pharmaceutical compounds.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective synthesis to create enantiomerically pure compounds.
• Agrochemical Research: Potential intermediate in the synthesis of novel pesticides or herbicides requiring specific chiral amine structures.
• Chemical Biology: Can be utilized in the synthesis of molecular probes and tool compounds for biological target identification and validation.

Basic Information

Product Name	cis-2-Methoxycyclopentan-1-Amine Hydrochloride
CAS No.	1431373-71-5
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	cis-1-Amino-2-methoxycyclopentane hydrochloride; (1R,2S)-2-Methoxycyclopentan-1-amine hydrochloride; (1S,2R)-2-Methoxycyclopentan-1-amine hydrochloride; 2-Methoxycyclopentan-1-amine hydrochloride (cis-); Cyclopentanamine, 2-methoxy-, hydrochloride, cis-; 2-Methoxy-1-cyclopentanamine hydrochloride; cis-2-Methoxy-1-cyclopentylamine hydrochloride
EINECS	Contact for details

Quality Control

Our cis-2-Methoxycyclopentan-1-Amine Hydrochloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including chiral purity verification. A Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and related substances is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.