Description

4,6-Dichloro-3-Iodo-Quinoline is a high-value halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Research: Used to develop new crop protection chemicals, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for organic semiconductors, ligands for catalysis, and functional dyes due to its electron-deficient aromatic system.
• Chemical Synthesis: Versatile substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitutions, enabling rapid diversification of chemical space.
• Academic & R&D: Essential reagent for methodological studies in organic chemistry and for probing structure-activity relationships (SAR).

Basic Information

Product Name	4,6-Dichloro-3-Iodo-Quinoline
CAS No.	1431364-37-2
Molecular Formula	C9H4Cl2IN
Molecular Weight	323.95 g/mol
Synonyms	3-Iodo-4,6-dichloroquinoline; 4,6-Dichloro-3-iodoquinoline; Quinoline, 4,6-dichloro-3-iodo-; 1431364-37-2
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-3-Iodo-Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.