Description

8-Bromo-4-Chloro-3-Iodo-Quinoline is a highly functionalized halogenated quinoline derivative, serving as a critical synthetic intermediate for advanced organic synthesis. Its unique multi-halogen substitution pattern makes it a valuable building block for constructing complex heterocyclic frameworks, particularly in medicinal chemistry and materials science. This compound is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other biologically active quinoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with unique modes of action.
• Material Science: Building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials due to the quinoline core.
• Ligand Synthesis: Serves as a starting material for synthesizing complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Useful for creating molecular probes and tags for studying biological systems and protein interactions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	8-Bromo-4-Chloro-3-Iodo-Quinoline
CAS No.	1431363-99-3
Molecular Formula	C9H4BrClIN
Molecular Weight	368.40 g/mol
Synonyms	3-Iodo-8-bromo-4-chloroquinoline; 8-Bromo-4-chloro-3-iodoquinoline; Quinoline, 8-bromo-4-chloro-3-iodo-; 4-Chloro-8-bromo-3-iodoquinoline; 1431363-99-3; SCHEMBL21883027; BRN 1431363-99-3
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloro-3-Iodo-Quinoline is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required by pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to minimize degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents (DMSO, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.