Description

6-Fluoro-2,3,4,9-Tetrahydro-1H-Carbazol-1-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the carbazole class of heterocyclic compounds. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries engaged in creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores with enhanced efficacy and selectivity.
• API Development: Serves as a core scaffold for the development of novel Active Pharmaceutical Ingredients (APIs) within the carbazole alkaloid family.
• Biochemical Research: Employed as a standard or reagent in biochemical assays and studies investigating enzyme inhibition or receptor binding.
• Process Chemistry & Scale-Up: Utilized in process development and optimization for the commercial-scale manufacturing of target molecules.

Basic Information

Product Name	6-Fluoro-2,3,4,9-Tetrahydro-1H-Carbazol-1-Amine
CAS No.	1429901-83-6
Molecular Formula	C12H13FN2
Molecular Weight	204.25 g/mol
Synonyms	6-Fluoro-1,2,3,4-tetrahydro-9H-carbazol-1-amine; 6-Fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-amine; 1-Amino-6-fluoro-1,2,3,4-tetrahydrocarbazole; 6-Fluoro-1,2,3,4-tetrahydrocarbazol-1-amine; 6-Fluoro-THCA; 6-F-THCA; 6-Fluoro tetrahydrocarbazolamine
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2,3,4,9-Tetrahydro-1H-Carbazol-1-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.