Description

5-Chloro-1-Cyclopropyl-1,4-Dihydro-6,7-Bis[(4-Methoxyphenyl)Methoxy]-4-Oxo-3-Quinolinecarboxylic Acid is a sophisticated, high-purity quinolinecarboxylic acid derivative designed for advanced research and development. This compound is valued for its complex molecular architecture, which serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation therapeutics, particularly in the areas of antimicrobial and anti-inflammatory agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Chemical Research: Used as a sophisticated scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Development: Serves as a critical precursor in the development and scale-up of new active pharmaceutical ingredients targeting bacterial infections.
• Biochemical Tool: Employed in biochemical assays to study enzyme inhibition mechanisms related to bacterial DNA gyrase and topoisomerase IV.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	5-Chloro-1-Cyclopropyl-1,4-Dihydro-6,7-Bis[(4-Methoxyphenyl)Methoxy]-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	1429440-05-0
Molecular Formula	C30H26ClNO7
Molecular Weight	548.0 g/mol (approx.)
Synonyms	5-Chloro-1-cyclopropyl-6,7-bis(4-methoxybenzyloxy)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 5-Chloro-1-cyclopropyl-6,7-di-O-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 6,7-Bis[(4-methoxyphenyl)methoxy]-5-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; Quinolonecarboxylic acid derivative (CAS 1429440-05-0); Advanced fluoroquinolone precursor intermediate.
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-1-Cyclopropyl-1,4-Dihydro-6,7-Bis[(4-Methoxyphenyl)Methoxy]-4-Oxo-3-Quinolinecarboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific client requirements or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere or with desiccant for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.