Description

5-Chloro-1-Ethyl-3-(Hydroxymethyl)-6,7-Bis((4-Methoxybenzyl)Oxy)Quinolin-4(1H)-One is a sophisticated quinoline derivative, a key synthetic intermediate in advanced pharmaceutical research and development. Its complex, multi-functional structure makes it a valuable building block for constructing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high molecular complexity. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, aiming to develop new drug candidates with optimized properties.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel quinoline-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential new therapeutics, from laboratory to pilot plant scale.
• Chemical Biology Probes: Can be utilized to develop tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A key material for fine chemical suppliers specializing in custom synthesis of complex, non-commercial molecules for clients.

Basic Information

Product Name	5-Chloro-1-Ethyl-3-(Hydroxymethyl)-6,7-Bis((4-Methoxybenzyl)Oxy)Quinolin-4(1H)-One
CAS No.	1429439-25-7
Molecular Formula	C28H28ClNO6
Molecular Weight	510.0 g/mol
Synonyms	5-Chloro-1-ethyl-3-(hydroxymethyl)-6,7-bis[(4-methoxyphenyl)methoxy]-1,4-dihydroquinolin-4-one; 6,7-Bis(4-methoxybenzyloxy)-5-chloro-1-ethyl-3-hydroxymethyl-4(1H)-quinolinone; 5-Chloro-1-ethyl-3-(hydroxymethyl)-6,7-bis(4-methoxybenzyloxy)quinolin-4(1H)-one; 4(1H)-Quinolinone, 5-chloro-1-ethyl-3-(hydroxymethyl)-6,7-bis[(4-methoxyphenyl)methoxy]-; CAS 1429439-25-7
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (by HPLC normalization)
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.