Description

8-Chloro-3-(Phenylsulfonyl)Quinoline is a high-value, synthetically versatile quinoline derivative characterized by its unique sulfonyl and chloro substituents. This compound serves as a critical advanced pharmaceutical intermediate and a specialized building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinoline scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a ligand precursor in catalysis due to its reactive chloro and sulfonyl groups.
• Material Science: Investigated for the creation of organic electronic materials, such as OLEDs or conductive polymers, where its planar structure and electron-withdrawing groups are beneficial.
• Chemical Research & Development: Serves as a standard or reference compound in methodological studies and for exploring new synthetic routes in academic and industrial R&D labs.

Basic Information

Product Name	8-Chloro-3-(Phenylsulfonyl)Quinoline
CAS No.	1429304-29-9
Molecular Formula	C15H10ClNO2S
Molecular Weight	303.76 g/mol
Synonyms	8-Chloro-3-(benzenesulfonyl)quinoline; 3-(Phenylsulfonyl)-8-chloroquinoline; Quinoline, 8-chloro-3-(phenylsulfonyl)-; 8-Chloro-3-phenylsulfonylquinoline; 1429304-29-9; 8-Chloro-3-(phenylsulfonyl)quinoline; 8-Chloro-3-(benzenesulphonyl)quinoline
EINECS	Contact for details

Quality Control

Our 8-Chloro-3-(Phenylsulfonyl)Quinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.