Description

Benzyl -1-Amino-6-Azaspiro[2.5]Octane-6-Carboxylic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting complex biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of innovative therapeutic agents, including potential treatments for central nervous system disorders and other specialized applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) with spirocyclic architectures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Protease Inhibitor Development: Serves as a core scaffold for designing inhibitors of specific enzymes, such as proteases involved in disease pathways.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological mechanisms and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	Benzyl -1-Amino-6-Azaspiro[2.5]Octane-6-Carboxylic Acid Hydrochloride
CAS No.	1428582-20-0
Molecular Formula	C15H20N2O2·HCl
Molecular Weight	296.79 g/mol (Free base: 260.33 g/mol)
Synonyms	1-Amino-6-(benzyloxycarbonyl)-6-azaspiro[2.5]octane hydrochloride; 6-[(Benzyloxy)carbonyl]-1-amino-6-azaspiro[2.5]octane hydrochloride; 6-CBZ-1-Amino-6-azaspiro[2.5]octane HCl; Benzyl 1-amino-6-azaspiro[2.5]octane-6-carboxylate hydrochloride; 1-Amino-6-azaspiro[2.5]octane-6-carboxylic acid benzyl ester hydrochloride; Z-1-Amino-6-azaspiro[2.5]octane-6-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our Benzyl -1-Amino-6-Azaspiro[2.5]Octane-6-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under inert atmosphere or with desiccant when appropriate to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.