Description

2-Amino-7-(5-Methyl-2-Thienyl)-7,8-Dihydroquinazolin-5(6H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused quinazolinone-thiophene structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for projects targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within R&D laboratories.
• Biochemical Reagent: Employed as a tool compound in biochemical assays to study specific enzyme interactions and cellular pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	2-Amino-7-(5-Methyl-2-Thienyl)-7,8-Dihydroquinazolin-5(6H)-One
CAS No.	1428139-24-5
Molecular Formula	C₁₄H₁₃N₃OS
Molecular Weight	271.34 g/mol
Synonyms	2-Amino-7-(5-methylthiophen-2-yl)-5,6,7,8-tetrahydroquinazolin-5-one; 7-(5-Methyl-2-thienyl)-2-amino-7,8-dihydro-5(6H)-quinazolinone; 1428139-24-5; 5(6H)-Quinazolinone, 2-amino-7,8-dihydro-7-(5-methyl-2-thienyl)-; 2-Amino-7-(5-methyl-2-thienyl)-5,6,7,8-tetrahydroquinazolin-5-one
EINECS	Contact for details

Quality Control

Our 2-Amino-7-(5-Methyl-2-Thienyl)-7,8-Dihydroquinazolin-5(6H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.