Description

1-[(4-Phenylpiperazin-1-Yl)Methyl]Cyclopropan-1-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropane and phenylpiperazine hybrid structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained cyclopropane ring and piperazine moiety.
• Ligand Synthesis: Serves as a precursor for the development of novel ligands targeting GPCRs (G-protein coupled receptors) and other biological targets.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Academic Research: Used in university and institutional labs for chemical biology and new synthetic methodology development.

Basic Information

Product Name	1-[(4-Phenylpiperazin-1-Yl)Methyl]Cyclopropan-1-Amine
CAS No.	1427990-44-0
Molecular Formula	C14H21N3
Molecular Weight	231.34 g/mol
Synonyms	1-[(4-Phenylpiperazin-1-yl)methyl]cyclopropanamine; 1-(4-Phenylpiperazin-1-ylmethyl)cyclopropylamine; Cyclopropanamine, 1-[(4-phenyl-1-piperazinyl)methyl]-; 1-((4-Phenylpiperazin-1-yl)methyl)cyclopropan-1-amine; 1-(Aminomethyl)cyclopropyl 4-phenylpiperazine; 1-(4-Phenylpiperazin-1-ylmethyl)cyclopropanamine
EINECS	Contact for details

Quality Control

Our 1-[(4-Phenylpiperazin-1-Yl)Methyl]Cyclopropan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant research and development activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.