Description

3-Trifluoromethoxybenzylhydrazine Dihydrochloride is a high-purity, specialty organic salt used as a critical building block in advanced chemical synthesis. This compound is valued for its role in introducing the trifluoromethoxybenzylhydrazine moiety, a key structural feature in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the hydrazine and trifluoromethoxy groups.
• Chemical Synthesis Reagent: Used in organic synthesis for the preparation of heterocyclic compounds, hydrazones, and other derivatives important in material science and fine chemical production.
• Ligand and Catalyst Development: Employed in the research and development of specialized ligands and catalysts for asymmetric synthesis and other catalytic processes.
• Academic & Industrial R&D: Essential for exploratory research in universities and corporate R&D laboratories focused on fluorine chemistry and novel molecular entities.

Basic Information

Product Name	3-Trifluoromethoxybenzylhydrazine Dihydrochloride
CAS No.	1427396-65-3
Molecular Formula	C8H10F3N2O·2HCl
Molecular Weight	283.09 g/mol (Free base: 206.18)
Synonyms	(3-(Trifluoromethoxy)phenyl)methanamine hydrazone dihydrochloride; 1-[(3-Trifluoromethoxyphenyl)methyl]hydrazine dihydrochloride; 3-(Trifluoromethoxy)benzylhydrazine dihydrochloride; (3-Trifluoromethoxybenzyl)hydrazine dihydrochloride; Hydrazine, [(3-(trifluoromethoxy)phenyl)methyl]-, dihydrochloride; CAS 1427396-65-3
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethoxybenzylhydrazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.