Description

2-Thia-6-Azaspiro[3.3]Heptane 2,2-Dioxide Hydrochloride is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery. This compound is valued for its unique spirocyclic sulfonamide structure, which serves as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of candidate drugs.
• Ligand and Probe Synthesis: Serves as a core structure for developing chemical probes and ligands in biochemical and pharmacological research.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	2-Thia-6-Azaspiro[3.3]Heptane 2,2-Dioxide Hydrochloride
CAS No.	1427388-39-3
Molecular Formula	C5H9ClN2O2S
Molecular Weight	196.65 g/mol
Synonyms	2-Thia-6-azaspiro[3.3]heptane 2,2-dioxide hydrochloride; 2-Thia-6-azaspiro[3.3]heptane, 2,2-dioxide, hydrochloride; 6-Azaspiro[3.3]heptane-2-sulfonic acid, 2,2-dioxide, hydrochloride; 2-Thia-6-azaspiro[3.3]heptane-2,2-dioxide HCl; Spiro[cyclopropane-1,2'-[1,2]thiazinane] 1,1-dioxide hydrochloride; 1,2-Thiazinane 1,1-dioxide, 3-azaspiro[2.2]pentane, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Thia-6-Azaspiro[3.3]Heptane 2,2-Dioxide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.