Description

Cyclohexanemethanamine, 4-Amino-, Hydrochloride (1:2) is a high-purity, dihydrochloride salt derivative of a functionalized cyclohexylmethylamine, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in providing a protected, stable, and readily soluble form of the primary amine for precise chemical transformations, particularly in regulated environments. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is utilized in the development of active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for asymmetric catalysis and metal complexes.
• Peptidomimetics Research: Incorporates the cyclohexylmethylamine scaffold into peptide analogs to enhance metabolic stability and bioavailability.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & R&D: Employed in university and corporate research labs for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	Cyclohexanemethanamine, 4-Amino-, Hydrochloride (1:2)
CAS No.	1427380-67-3
Molecular Formula	C7H16N2 · 2HCl
Molecular Weight	209.14 g/mol (Free base: 128.22)
Synonyms	4-Aminocyclohexanemethanamine Dihydrochloride; (4-Aminocyclohexyl)methanamine Dihydrochloride; 1,4-Cyclohexanedimethanamine, 4-Amino-, Dihydrochloride; 4-Amino-1-cyclohexanemethanamine Dihydrochloride; 4-Aminomethylcyclohexylamine Dihydrochloride; 4-(Aminomethyl)cyclohexanamine Dihydrochloride; trans/cis-4-(Aminomethyl)cyclohexanamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our Cyclohexanemethanamine, 4-Amino-, Hydrochloride (1:2) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, residual solvents, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.