Description

1-(2,3-Difluorophenyl)Ethan-1-Amine Hydrochloride is a high-purity fluorinated amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic amine scaffold with enhanced reactivity and metabolic stability for pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluorophenyl group can improve biological activity and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Useful for creating molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	1-(2,3-Difluorophenyl)Ethan-1-Amine Hydrochloride
CAS No.	1427378-79-7
Molecular Formula	C8H10ClF2N
Molecular Weight	193.62 g/mol
Synonyms	1-(2,3-Difluorophenyl)ethanamine hydrochloride; α-Methyl-2,3-difluorobenzylamine hydrochloride; 1-Aminoethyl-2,3-difluorobenzene hydrochloride; (2,3-Difluorophenyl)ethylamine HCl; 2,3-Difluoro-α-methylbenzylamine hydrochloride; 1-(2,3-Difluorophenyl)ethylamine hydrochloride; 2,3-Difluoroamphetamine hydrochloride (contextual); Contact for additional names.
EINECS	Contact for details

Quality Control

Our 1-(2,3-Difluorophenyl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.