Description

2-Chloro-6-Fluoro-4-Methylbenzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily required by manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the biological activity of the chloro-fluoro substitution pattern.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing complex organic molecules used in electronic displays and optoelectronic devices.
• Organic Synthesis Building Block: A versatile reagent for introducing substituted benzoic acid motifs into larger molecular architectures via coupling, esterification, and amidation reactions.
• Research & Development (R&D): Essential for medicinal chemistry and process chemistry research in academic and industrial laboratories.
• Dye & Pigment Intermediate: Used in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	2-Chloro-6-Fluoro-4-Methylbenzoic Acid
CAS No.	1427373-49-6
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	2-Chloro-6-fluoro-p-toluic acid; 4-Methyl-2-chloro-6-fluorobenzoic acid; Benzoic acid, 2-chloro-6-fluoro-4-methyl-; 6-Fluoro-2-chloro-4-methylbenzoic acid; 2-Chloro-6-fluoro-4-methyl-benzoic acid; 2-Chloro-6-fluoro-4-methylbenzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-4-Methylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.