Description

Benzoic Acid, 4-Chloro-5-Fluoro-2-Methyl- is a high-purity, multi-substituted benzoic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile halogenated aromatic scaffold for constructing complex molecules with tailored properties. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of its halogenated structure.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its functionalized aromatic core.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions, esterifications, and amide bond formations to introduce a substituted benzoic acid moiety.

Basic Information

Product Name	Benzoic Acid, 4-Chloro-5-Fluoro-2-Methyl-
CAS No.	1427365-67-0
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	4-Chloro-5-fluoro-2-methylbenzoic acid; 2-Methyl-4-chloro-5-fluorobenzoic acid; 4-Chloro-5-fluoro-o-toluic acid; 2-Methyl-4,5-difluorobenzoic acid (isomer); Benzoic acid, 4-chloro-5-fluoro-2-methyl-; 4-Cl-5-F-2-Me-BA; 4,5-Disubstituted-2-methylbenzoic acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Chloro-5-Fluoro-2-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.