Description

1,2,3,4-Tetrahydro-Quinolin-8-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its role as a key synthon in the synthesis of complex heterocyclic molecules, particularly in medicinal chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and plant growth regulators due to its heterocyclic quinoline core.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex nitrogen-containing heterocycles and functionalized amines in academic and industrial R&D.
• Material Science: Potential application in the synthesis of organic ligands for catalysts or in the development of specialty polymers and dyes.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	1,2,3,4-Tetrahydro-Quinolin-8-Ylamine Hydrochloride
CAS No.	1427195-46-7
Molecular Formula	C9H13ClN2
Molecular Weight	184.67 g/mol
Synonyms	8-Amino-1,2,3,4-tetrahydroquinoline hydrochloride; 1,2,3,4-Tetrahydro-8-quinolinamine hydrochloride; 8-Aminotetrahydroquinoline HCl; THQ-8-amine HCl; 8-Amino-THQ hydrochloride; 1,2,3,4-Tetrahydroquinolin-8-amine hydrochloride; 1427195-46-7
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-Quinolin-8-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.