Description

2-Aza-Bicyclo[4.1.0]Heptane Hydrochloride is a high-purity, nitrogen-containing bicyclic building block, specifically a strained aziridine derivative. This compound is of significant value in medicinal chemistry and organic synthesis as a versatile intermediate for constructing complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Scaffold: Used to introduce the strained, three-membered aziridine ring into lead compounds, enabling structure-activity relationship (SAR) studies and probing biological activity.
• Agrochemical Research: Serves as a building block in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Academic & Industrial R&D: Employed in methodological research for new ring-opening and functionalization reactions due to its reactive aziridine moiety.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the incorporation of a bicyclic amine framework.

Basic Information

Product Name	2-Aza-Bicyclo[4.1.0]Heptane Hydrochloride
CAS No.	1427195-18-3
Molecular Formula	C6H12ClN
Molecular Weight	133.62 g/mol
Synonyms	2-Azabicyclo[4.1.0]heptane hydrochloride; 1-Azabicyclo[4.1.0]heptane hydrochloride; Bicyclo[4.1.0]heptane, 2-aza-, hydrochloride; 2-Azabicyclo[4.1.0]heptane, hydrochloride; 2-Aza-bicyclo[4.1.0]heptane HCl; 2-Azabicyclo[4.1.0]heptane HCl salt
EINECS	Contact for details

Quality Control

Our 2-Aza-Bicyclo[4.1.0]Heptane Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods are validated to meet the stringent requirements of pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.