Description

Benzene, 2-Bromo-1-Chloro-3-Fluoro-5-Nitro- is a highly functionalized, multi-halogenated nitrobenzene derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block for complex organic synthesis. Its unique substitution pattern makes it invaluable for introducing specific halogen and nitro functionalities into target molecules, enabling the development of novel compounds with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated nitroaromatic compounds.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and halogen groups.
• Organic Synthesis Reagent: Serves as a substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, enabling complex molecular architecture construction.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized azo dyes and colorants.
• Academic and R&D Laboratories: Essential for methodological studies and exploring new chemical reactions involving polyhalogenated aromatics.

Basic Information

Product Name	Benzene, 2-Bromo-1-Chloro-3-Fluoro-5-Nitro-
CAS No.	1426805-15-3
Molecular Formula	C6H2BrClFNO2
Molecular Weight	254.44 g/mol
Synonyms	1-Bromo-2-chloro-3-fluoro-5-nitrobenzene; 2-Bromo-1-chloro-3-fluoro-5-nitrobenzene; 3-Fluoro-5-nitro-2-bromo-1-chlorobenzene; 2-Bromo-1-chloro-3-fluoro-5-nitro-benzene; Benzene, 1-bromo-2-chloro-3-fluoro-5-nitro-; (2-Bromo-1-chloro-3-fluoro-5-nitrophenyl); Polyhalogenated Nitrobenzene Derivative
EINECS	Contact for details

Quality Control

Our Benzene, 2-Bromo-1-Chloro-3-Fluoro-5-Nitro- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards of cGMP and ISO guidelines where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.